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InChiKey: VVZNWYXIOADGSW-UHFFFAOYSA-N
[Epub ahead of print] PubMed PMID: 30571144
CAS Number: 256925-03-8
is a BET bromodomain antagonist
or dexamethasone triggered synergistic anti-MM activity
Pyridostatin TFA salt - CAS# 1085412-37-8 167 InChiKey: VVZNWYXIOADGSW-UHFFFAOYSA-NPyridostatin, CAS No. 1085412 37 8, stabilizes G quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). Pyridostatin promotes growth arrest in human cancer cells by inducing replication and transcription dependent DNA damage. Pyridostatin targets gene bodies containing clusters of sequences with a propensity for G quadruplex formation. As a result, pyridostatin modulated the expression
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